Barbara Wirthl, M.Sc.

Research interests

Wirthl B.*, Hervas-Raluy S.*, Enrique Guerrero P., Robalo Rei G., Nitzler J., Coronado E., Font de Mora J., Schrefler B. A., Gomez-Benito M. J., Garcia-Aznar J. M., Wall W.A. (2023), Tumour growth: An approach to calibrate parameters of a multiphase porous media model based on in vitro observations of Neuroblastoma spheroid growth in a hydrogel microenvironment, Computers in Biology and Medicine, 106895. doi:10.1016/j.compbiomed.2023.106895 (*co-first authorship)

Wirthl B., Brandstaeter S., Nitzler J. Schrefler B.A., Wall W.A. (2022), Global sensitivity analysis based on Gaussian-process metamodelling for complex biomechanical problems, Int J Numer Meth Biomed Engng., 39(3):e3675. doi:10.1002/cnm.3675

Wirthl B.*, Kremheller J.*, Schrefler B.A., Wall W. A. (2020), Extension of a multiphase tumour growth model to study nanoparticle delivery to solid tumours, PLOS ONE, 15(2):e0228443, doi:10.1371/journal.pone.0228443 (*co-first authorship)

Fletcher, T.L., Wirthl, B., Kolias, A.G. et al. (2016), Modelling of Brain Deformation After Decompressive Craniectomy. Ann Biomed Eng 44, 3495–3509, doi:10.1007/s10439-016-1666-7

Supervised Student Projects 
  • Computational Modelling of in Vitro Tumour Growth: From Imaging Data to Bayesian Inverse Analysis, Term Paper
  • A Bayesian Inference Approach for Optimal Tumour Treatment Using Gaussian Processes, Term Paper (co-supervised with Jonas Nitzler)
  • A study of pharmacokinetics and pharmacodynamics in a multiphase tumour growth model, MSE research internships (co-supervised with Johannes Kremheller)
  • 3D Visualisation of tumour growth, Visualization Techniques in Computational Mechanics
  • Output Monitoring Routines for Parameter Studies in a Finite Element Tumour Growth Model, Bachelor's Thesis (co-supervised with Johannes Kremheller)
  • since 2018 Research Associate at the Institute for Computational Mechanics (Lehrstuhl für Numerische Mechanik), Technische Universität München, Germany
  • 2018 Master of Science (M.Sc.), Mechanical Engineering, Technische Universität München, Germany

3D Visualisation of a solid tumour with nanoparticles (Visualization Techniques in Computational Mechanics)