Dr.-Ing. Lena Yoshihara (née Wiechert)

Contact

Teaching

Research Interests

Awards

  • Timoshenko-Föppl Award for PhD thesis (2012)
  • ECCOMAS PhD Award (2011) 
  • Heinz-Peter-Scholz Award for diploma thesis (2006)

Scientific Community

  • Executive board member of collaborative research center SFB Transregio 40/TRR 40 (Fundamental Technologies for the Development of Future Space-Transport-System Components under High Thermal and Mechanical Loads), 2012-2013
  • Secretary of the German Association for Computational Mechanics (GACM), 2012-2013
  • Secretary of the ECCOMAS CFD Committee

Publications

Articles in Peer-Reviewed International Journals 

  • C. J. Roth, L. Yoshihara, and W. A. Wall: Computational Modeling of Respiratory Biomechanics. In R. Narayan (Ed.), Encyclopedia of Biomedical Engineering, vol. 2, pp. 70–80. Elsevier, 2019.
  • A. D. Rauch, A.-T. Vuong, L. Yoshihara, and W. A. Wall: A coupled approach for fluid saturated poroelastic media and immersed solids for modeling cell-tissue interactions. International Journal for Numerical Methods in Biomedical Engineering, accepted, 2018.
  • J. Kremheller, A.-T. Vuong, L. Yoshihara, W. A. Wall, and B. A. Schrefler: A monolithic multiphase porous medium framework for (a-)vascular tumor growth. Computer Methods in Applied Mechanics and Engineering 340: 657-683, 2018
  • A. M. Birzle, C. Martin, L. Yoshihara, S. Uhlig, and W. A. Wall: Experimental characterization and model identification of the nonlinear compressible material behavior of lung parenchyma. Journal of the Mechanical Behavior of Biomedical Materials 77: 754-763, 2018.
  • C. J. Roth, L. Yoshihara, and W. A. Wall: A simplified parametrised model for lung microstructures capable of mimicking realistic geometrical and mechanical properties. Computers in Biology and Medicine 89: 104-114, 2017.
  • C. J. Roth, L. Yoshihara, M. Ismail, and W. A. Wall: Computational modelling of the respiratory system: Discussion of coupled modelling approaches and two recent extensions. Computer Methods in Applied Mechanics and Engineering 33: e02787, 2017.
  • L. Yoshihara, C. J. Roth, and W. A. Wall: Fluid-structure interaction including volumetric coupling with homogenised subdomains for modeling respiratory mechanics. International Journal for Numerical Methods in Biomedical Engineering 33: e2812, 2017.
  • F. Verdugo, C. J. Roth, L. Yoshihara, and W. A. Wall: Efficient solvers for coupled models in respiratory mechanics. International Journal for Numerical Methods in Biomedical Engineering 33: e02795, 2017.
  • C. J. Roth, M. Ismail, L. Yoshihara, and W. A. Wall: A comprehensive computational human lung model incorporating inter-acinar dependencies: Application to spontaneous breathing and mechanical ventilation. International Journal for Numerical Methods in Biomedical Engineering 33: e02787, 2017.
  • A. Vuong, L. Yoshihara, and W. A. Wall: A general approach for modeling interacting flow through porous media under finite deformations. Computer Methods in Applied Mechanics and Engineering 283: 1240-1259, 2015
  • L. Yoshihara, M. Coroneo, A. Comerford, G. Bauer, T. Klöppel, and W. A. Wall: A combined fluid-structure interaction and multi-field scalar transport model for simulating mass transport in biomechanics. International Journal for Numerical Methods in Engineering 100: 277-299, 2014http://mediatum.ub.tum.de/?id=1140393
  • M. Coroneo, L. Yoshihara, L., and W. A. Wall: Biofilm growth: a multi-scale and coupled fluid-structure interaction and mass transport approach. Biotechnology and Bioengineering 111: 1385-1395, 2014
  • C. Danowski, V. Gravemeier, L. Yoshihara, and W. A. Wall: A monolithic computational approach to thermo-structure interaction. International Journal for Numerical Methods in Engineering 95: 1053-1078, 2013
  • V. Gravemeier, A. Comerford, L. Yoshihara, M. Ismail, and W. A. Wall: A novel formulation for Neumann inflow boundary conditions in biomechanics. International Journal for Numerical Methods in Biomedical Engineering 28: 560-573, 2012
  • C. Dassow, L. Wiechert, C. Martin, S. Schumann, G. Müller-Newen, O. Pack, J. Guttmann, W. A. Wall, and S. Uhlig: Biaxial distension of precision-cut lung slices. Journal of Applied Physiology 108:713-721, 2010
  • W. A. Wall, L. Wiechert, A. Comerford, and S. Rausch: Towards a comprehensive computational model for the respiratory system. International Journal for Numerical Methods in Biomedical Engineering  26:807-827, 2010
  • L. Wiechert and W. A. Wall: A nested dynamic multi-scale approach for 3D problems accounting for micro-scale multi-physics. Computer Methods in Applied Mechanics and Engineering 199:1342-1351, 2010
  • L. Wiechert, R. Metzke and W. A. Wall: Modeling the mechanical behavior of lung tissue at the micro-level. Journal of Engineering Mechanics 135:434-438, 2009

Articles in Other Journals

  • L. Yoshihara, W. A. Wall, and M. W. Gee: Die virtuelle Lunge. Akademie Aktuell 02/2012: 58-61, 2012
  • W. A. Wall, L. Wiechert, A. Comerford, and S. Rausch: Computational modeling of the respiratory system. IACM expressions 25:32-36, 2009

Book Chapters

  • L. Yoshihara, M. Ismail, and W. A. Wall: Bridging Scales in Respiratory Mechanics. Computer Models in Biomechanics - From Nano to Macro, Springer, 395-408, 2012
  • L. Wiechert, A. Comerford, S. Rausch, and W. A. Wall: Advanced Multi-Scale Modelling of the Respiratory System. Fundamental Medical and Engineering Investigations on Protective Artificial Respiration, Springer, 1-32, 2011
  • A. Comerford, S. Rausch, L. Wiechert, M. W. Gee, and W. A. Wall: Computational modelling of the respiratory system for improvement of mechanical ventilation strategies. High Performance Computing in Science and Engineering, Garching/Munich 2009, Springer, 267-277, 2010
  • L. Wiechert, T. Rabczuk, M. W. Gee, R. Metzke, and W. A. Wall: Coupled problems in computational modeling of the respiratory system. High Performance Computing on Vector Systems 2007, Springer, 145-166, 2007

Thesis

Conference Proceedings

  • W. A. Wall, L. Wiechert, A. Comerford, S. Rausch, M. W. Gee, and A. Maier: Towards Clinical Impact Through Computational Biomechanics. Proceedings of the 2nd South-East European Conference on Computational Mechanics SEECM2009, Rhodes, Greece, June 22-24, 2009
  • W. A. Wall, A. Comerford, L. Wiechert, and S. Rausch: Coupled and multi-scale building blocks for a comprehensive computational lung model. Proceedings of the ASME Summer Bioengineering Conference 2009, Lake Tahoe, USA, June 17-21, 2009
  • L. Wiechert, T. Rabczuk, A. Comerford, R. Metzke, and W. A. Wall: Towards stresses and strains in the respiratory system. European Series in Applied and Industrial Mathematics Proceedings 23:98-113, 2008
  • W. A. Wall, L. Wiechert, T. Rabczuk, and R. Metzke: Coupled problems in computational modeling of the respiratory system. Proceedings of the International Conference on Computational Methods for Coupled Problems in Science and Engineering (Coupled Problems 2007), M. Papadrakakis, E. Onate, B. Schrefler (Eds.), Santa Eulalia, Spain, May 21-23, 2007

Invited Presentations 

  • L. Yoshihara: Computational modeling of multi-field and multi-scale phenomena in respiratory mechanics (semi-plenary keynote). ECCOMAS Young Investigators Conference, Aveiro, Portugal, 2012
  • L. Wiechert and W. A. Wall: Computational modeling of respiratory mechanics - Bridging scales from alveolar to organ level. International Conference on Computational Plasticity, Barcelona, Spain, 2011
  • L. Wiechert and W. A. Wall: Computational modeling of multi-scale phenomena in respiratory mechanics. Annual Meeting of the GAMM, Graz, Austria, 2011
  • L. Wiechert and W. A. Wall: Building blocks of a comprehensive computational lung model. 3. Dresdner Medizintechnik-Symposium, Dresden, Germany, 2010
  • L. Wiechert, A. Comerford, S. Rausch, and W. A. Wall: Computational modeling of multi-field and multi-scale phenomena in respiratory mechanics. 2nd German-Japanese Workshop on Computational Mechanics, Yokohama, Japan, 2010
  • L. Wiechert and W. A. Wall: A coupled multi-scale approach for modeling lung tissue stretching. 2nd Aachen Symposium on Natural and Artificial Ventilation, Aachen, Germany, 2009
  • L. Wiechert and W. A. Wall: Multi-scale modeling of coupled fluid-tissue problems in the respiratory system. 3rd GACM Colloquium on Computational Mechanics, Hannover, Germany, 2009
  • L. Wiechert and W. A. Wall: Multi-scale modeling of lung parenchyma. 1st Aachen Symposium on Natural and Artificial Respiration, Aachen, Germany, 2008
  • L. Wiechert and W. A. Wall: Multi-scale analysis of coupled lung tissue dynamics. World Congress on Computational Mechanics, Venice, Italy, 2008
  • L. Wiechert and W. A. Wall: Computational modeling of pulmonary alveoli against the background of multi-scale analyses of the respiratory system. 2nd GACM Colloquium on Computational Mechanics, Garching, Germany, 2007
  • L. Wiechert and W. A. Wall: Computational modeling of pulmonary alveoli. US National Congress on Computational Mechanics, San Francisco, USA, 2007
  • L. Wiechert, M. W. Gee, T. Rabczuk, and W. A. Wall: Coupled problems in computational modeling of the respiratory system. 6th Teraflop Workshop, HLRS, Stuttgart, Germany, 2007

Other Presentations 

  • L. Yoshihara, A. Comerford, G. Bauer, T. Klöppel, A.-T. Vuong, and W. A. Wall: Computational modeling of transport phenomena in biomechanics. European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS), Vienna, Austria, 2012
  • L. Yoshihara, M. Coroneo, and W. A. Wall: A computational approach for transport in biological fluid-structure systems as a basis for advanced growth modeling. European Solid Mechanics Conference, Graz, Austria, 2012
  • L. Wiechert and W. A. Wall: Coupling of scales in a comprehensive continuum mechanics based computational lung model. BMES Annual Meeting, Austin, USA, 2010
  • L. Wiechert, S. Rausch, and W. A. Wall: Multi-scale modeling of lung parenchyma. International Conference on Computational Bioengineering, Bertinoro, Italy, 2009
  • L. Wiechert and W. A. Wall: Dynamic multi-scale modeling of lung parenchyma. International Conference on Computational Plasticity, Barcelona, Spain, 2009
  • L. Wiechert, R. Metzke, and W. A. Wall: Towards multi-scale analyses of lung parenchyma. ECCOMAS Thematical Conference on Multi-scale Computational Methods for Solids and Fluids, Cachan, France, 2007
  • L. Wiechert, R. Metzke, and W. A. Wall: Computational modeling of pulmonary alveoli. 32. Bayerisch-Tirolerisches Mechanik Kolloquium, Munich, Germany, 2007